It's an experiment in human behavior. It's an exploration of the most natural of animal impulses. It's something new under the moon. And it bites. When security dispatcher Aaron Scates is blinded in an explosion, he's put in the care of Dr. Andrea Hewlitt, famous in her field for spearheading extraordinary-though controversial-medical breakthroughs. Her newest is cross-species organ transplants, and Aaron is her first human subject. When a severely wounded wolf is brought to Dr. Hewlitt's office by museum curator Lydia Armstrong, Dr. Hewlitt leaps on the opportunity and successfully transplants the wolf's eyes to Aaron-despite Lydia's objections. Aaron, however, is thrilled. Not only can he see again, he can see in the dark. He also has an unusually acute sense of hearing, and tears into a raw steak like never before. Unfortunately, he also tends growl...

Follows a group of friends that decide to go snowmobiling during their winter break. They make a "wrong turn", getting lost in a storm, and seek shelter in an abandoned sanatorium. They are completely isolated by the storm and are thankful they can get out of the elements. But the sanatorium has a troubled past, and some of its former patients still reside there and are not happy about the intrusion. In a deadly game of cat and mouse, the college kids must fight to survive the night.